| Champion |
Missouri Fury 04
(7-1-0 in 2021)
National Qualified
State Qualified
|
16A
|
New Melle, MO
|
| Runner-Up |
StL Sparks
(16-13-2 in 2021)
National Qualified
State Qualified
|
18B
|
Florissant, MO
|
| |
Aftermath Fastpitch
(14-11-1 in 2021)
|
18B
|
Foristell, MO
|
| |
Cyclones
(16-27-0 in 2021)
|
18B
|
Imperial, MO
|
| |
Lady Bulldogs Elite
(6-10-1 in 2021)
|
18B
|
Rolla, MO
|
| |
Midland Bandits Franzen/Reynolds
(20-11-4 in 2021)
National Qualified
State Qualified
|
18B
|
Saint Peters, MO
|
| |
St. Louis Academy 18u
(17-17-1 in 2021)
|
18B
|
Arnold, MO
|
| |
STL Heat 04 - Zimmer
(16-8-0 in 2021)
|
18B
|
St. Louis, MO
|
| |
Stl Nemesis 18u
(9-21-1 in 2021)
|
18B
|
St. Charles, MO
|